نمونه ترجمه تخصصی پزشکی درباره ترانکسامیک اسید در کاهش خونریزی حین و بعد از عمل جراحی سنگ کلیه از طریق پوست

tranexamic acid on bleeding control during and after percutaneous nephrolithotomy

The highest frequency of stone in the both groups was at the lower and mid kidney and there was no significant difference between the two groups in terms of normal and attenuated kidney parenchyme. Siddiq et al. reported that the highest frequency of stone was at the lower and pelvic areas, while there was no significant difference between the intervention and control groups. Their findings are consistent with the present findings [9]. Hospitalization term and the need for blood injection were significantly lower in the intervention group compared to the control group. In addition, pre/intraoperative hemoglobin levels in the two groups were not significantly different. On the other hand, postoperative hemoglobin, liquid hemoglobin, and hemoglobin count decline in the intervention group was significantly lower than that of the control group. Mohammadi et al. reported that the mean level of postoperative hemoglobin in TXA group was significantly higher than that in the control group (normal saline) [10]. Yao et al. studied patients with polycystic and showed that bleeding term and the volume of injected blood in TXA patients was significantly lower than those in the control group [11]. Mihai et al. showed that the need for blood injection in the intervention group was less than that in the control group and that the use of TXA in PCNL was safe, economic, and acceptable [12]. Siddiq et al. reported that hemoglobin and hematocrit levels in intervention and control groups were not significantly different and the mean level of changes in hemoglobin level in the placebo group after the operation was higher than that of the intervention group. They also showed that the need for blood injection in TXA group was significantly less than the placebo group [9]. Using TXA in PCNL operation attenuates bleeding and hemoglobin loss. Studies have shown that a decrease in intraoperative bleeding decreases the operation time duration, mortality rate, and side-effects in patients [13, 14]. Yao et al. reported that creatinine serum level and eGFR in TXA group were at desirable levels [11]. The results showed that there was no thrombotic side-effect in the intervention group and non-thrombotic side-effects were observed in 38 patients (70.4%) as nausea and 16 patients (29.6%) as vomiting. Rashid et al. reported that the side-effects in the intervention group were bleeding (4%), PCS rapture (4%), and UTI and fever (16%); and in group B were bleeding (8%), PCS rapture (8%), and UTI and fever (20%). These differences are not significant [15]. As the results showed, postoperative fever is one of the most common side-effects of PCNL (32.7%) and sepsis rate ranges from 0.97% to 4.7% [16].