The effects of hyssop essence on immunohematology factors of blood
Herbal plants have been long used as a valuable natural sources for obtaining medicines with no side-effect to man. According to statistics, the effective ingredients of more than 50% of drugs in the market are of plant source [1]. Among different countries, Iran with diverse climates is one of the richest sources of herbal medicines in the world [2]. One of the most important and valuable herbs in Iran is hyssop [3]. The origin of the plant is from Anatolia so that it can be found in a region from the Caspian Sea to the Black Sea as well as sandy Mediterranean regions [4]. There are different species of hyssop and only hyssop angustifolius is found in Iran. The useful parts of the plant are the branches with flower; while in some regions, all parts of the plants are used [5]. The chemical compounds found in the plant vary depending on the place and condition of growth. Different compounds like flavonoids, tannin, thymol, charoechrol, mirtnic acid, and pinic acid are found in the plant essence. Each one of these compounds have different therapeutic effects such as antibacterial, antifungal, anti-inflammation, and painkilling effect [6]. Salehi et al. examined painkilling and anti-inflammation effects of hyssop ethanol essence in mice. The results showed that ethanol essence of hyssop can control pain and inflammation in small lab mice [7]. Hou et al. (2009) found that long-term use of the plat can inhibit secretion of eotaxin 2, which is a factor in inflammatory response in asthma patients. Therefore, the plant attenuates inflammation response in these patients [8]. Hyssop contains mucilage compounds and volatile compounds like pinkokamphan, alpha, betapinin, Kamphan, and sezkoitrephen alcohol that are good for the respiration system. The plant can be used to prevent respiratory infection, asthma, and bronchitis [9]. Moreover, flavonoid compounds in the plant prevent antioxidant effects [10]. Dzamic et al. (2013) in-vitro examined hyssop plant and showed its antioxidant effects, which can be used in food and pharmaceutical industries [10]. Tehranipour et al. (2017) showed that alcoholic essence of hyssop has healing effect on the spine frontal tip neurons of the rat after creating a lesion. This effect can be explained by antioxidant and anti-inflammation effects of hyssop [11]. Tannin, several phenol compound, and various organic acid in hyssop create considerable antibacterial effect [12]. Another study examined antibacterial effect of hyssop essence on E-coli, Staphylococcus aureus, and listeria monocytogenes and showed that hyssop controlled the bacteria [13]. Kizil et al. (2010) examined antibacterial effect of hyssop collected from the southeast of Anatolia and reported that the essence has a notable antibacterial activity against microorganisms [12].
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