نمونه ترجمه تخصصی بهداشت حرفه ای درباره رشد و پاتوبیوشیمی ناشی ازمصرف لازالوسید و فلورفنیکل

growth and pathobiochemical indices in broiler chicken due to the use of lasalocid and fluorophenykel the

A wide range of antimicrobials are used by poultry industries in different countries [3, 4]. The antimicrobials are natural or synthesized factors that can kill microorganisms or inhibit their growth. The antimicrobials are one of the essential tools in the poultry industry to treat and control bacterial infections. The mutual relationships between bacteria, antimicrobial factors, the host, and the simultaneous administration are determinant factors in designing logical plans of administering drugs [1]. Felorfenicol affects several negative gram and positive gram organisms such as some strains resistive to chloramphenicol, E. coli, salmonella typhimurium, and staphylococcus aureus. Through inhibiting protein synthesis, it can inhibit peptidyl transferases enzyme [9, 10]. Felorfenicol belongs to wide spectrum antibiotic group with a structure that is similar to chloramphenicol; however, despite chloramphenicol it does not cause aplastic anemia thanks to lack of O-nitro group. Long-term use, however, might degrade bone morrow (Ben et al., 2019). Felorfenicol is similar to chloramphenicol in terms of activity and range of effect and it is more active in some cases compared to chloramphenicol. Since hydroxyl group is replaced with fluorine molecule, felorfenicol is less resistive to bacteria with chloramphenicol acetyltransferases [2]. Wide and relatively more intensive pharmaceutical activity of the drug compared to chloramphenicol; the fact that there are fewer cases resistive to felorfenicol; and since felorfenicol does no create aplastic anemia when the right dose and term are observed have made felorfenicol a popular choice in poultxry industry (2, 3). Lasalocid is one of the ionophore coccidiostats used to control coccidiostats in chicken and turkey. The compound is also featured with selective antimicrobial activity against positive gram bacteria [14, 15]. Compared to other ionophore drugs, lasalocid has a higher safety factor and is more compatible with other additive and drug materials (Novilla, 2018).